Rhamnus davurica leaf extract inhibits Fyn activation by antigen in mast cells for anti-allergic activity

Kim, Ji Hyung; Kim, A-Ram; Kim, Hyuk Soon; Kim, Hyun Woo; Park, Young Hwan; You, Jueng Soo; Park, Yeong Min; Her, Erk; Kim, Hyung Sik; Kim, Young Mi; Choi, Wahn Soo

doi:10.1186/s12906-015-0607-6

BMC Complementary Medicine and Therapies

Table 1 Effects of plant extracts on the Ag-induced degranulation in RBL-2H3 mast cells

From: Rhamnus davurica leaf extract inhibits Fyn activation by antigen in mast cells for anti-allergic activity

Plant name	Part extracted	Voucher specimen number	Percent inhibition of degranulation^a
Acer okamotoanum	Stem-bark	016-081	0.00
Acer ukurunduense	Leaf	016-050	40.78
Acer ukurunduense	Stem	016-051	30.32
ActinoStemma lobatum	Whole plant	017-038	18.48
Ardisia pusilla	Whole plant	016-061	0.00
Aster incisa	Whole plant	016-001	0.00
Berberis amurensis var. quelpaertensis	Stem	016-069	16.96
Betula chinensis	Leaf	017-013	39.17
Betula chinensis	Stem	017-014	27.76
Betula davurica	Stem	017-045	3.78
Betula davurica	Stem-bark	017-046	0.00
Betula ermani var. saitoana	Leaf	016-089	10.80
Betula ermani var. saitoana	Stem	016-090	1.78
Boehmeria pannosa	Whole plant	016-080	0.43
Bupleurum longeradiatum	Whole plant	017-016	29.22
Cacalia auriculata var. matsumurana	Whole plant	016-047	12.05
Campylotropis macrocarpa	Aboveground part	017-023	0.00
Celosia argentea	Whole plant	017-012	38.14
Chaenomeles sinensis	Leaf	017-040	3.85
Cinnamomum loureirii	Leaf	016-082	5.92
Clerodendrum trichotomum	Leaf	016-026	2.27
Clintonia udensis	Whole plant	016-019	51.37
Corydalis heterocarpa	Whole plant	016-079	11.79
Crataegus scabrida	fruit	017-047	0.00
Cyrtomium falcatum	Aboveground part	016-028	4.84
Daphniphyllum macropodum	Leaf	017-019	6.46
Daphniphyllum macropodum	Stem	017-020	0.29
Deutzia prunifolia	Stem	017-051	44.69
Dicentra spectabilis	Aboveground part	016-010	8.22
Diospyros kaki	Leaf	017-007	17.98
Diospyros kaki	Stem	017-008	17.68
Diospyros kaki	Stem-bark	017-009	17.25
Diospyros kaki	Root	017-011	11.64
Dryopteris championi	Whole plant	016-088	6.97
Elaeagnus macrophylla	Leaf	017-059	23.52
Forsythia nakaii	Leaf	016-085	1.93
Fraxinus sieboldiana	Leaf	017-073	9.30
Geranium wilfordii	Whole plant	017-070	42.07
Houttuynia cordata	Whole plant	016-077	7.45
Hydrangea serrata for. acuminata	Aboveground part	016-058	67.16
Hypericum erectum	Whole plant	017-018	6.53
Kalopanax pictus	Stem-heartwood	016-083	14.84
Lilium lancifolium	Aboveground part	016-091	8.82
Lindera erythrocarpa	Leaf	016-054	18.09
Lindera erythrocarpa	Stem	016-055	14.20
Lindera obtusiloba	Stem	016-063	19.80
Lycopodium clavatum var. nipponicum	Whole plant	017-069	23.56
Lycoris aurea	Underground part	017-015	52.03
Melandryum seoulense	Whole plant	017-003	62.76
Monochoria vaginalis var. plantaginea	Whole plant	017-043	2.84
Mosla punctulata	Whole plant	017-037	6.83
Nandina domestica	Leaf	016-023	6.46
Nuphar japonicum	Whole plant	016-006	9.22
Oenothera laciniata	Whole plant	016-075	14.50
Pedicularis resupinata	Whole plant	017-072	35.15
Perilla frutescens var. acuta	Whole plant	017-071	14.14
Persicaria fauriei	Whole plant	018-003	28.89
Persicaria thunbergii	Whole plant	017-017	17.79
Phlomis koraiensis	Aboveground part	017-064	19.72
Phlomis koraiensis	Underground part	017-065	1.94
Phtheirospermum japonicum	Whole plant	017-024	27.81
Picris hieracioides var. glabrescens	Whole plant	017-074	16.13
Polystichum polyblepharum	Whole plant	016-020	0.99
Potentilla dickinsii	Whole plant	017-036	7.18
Prunus sargentii	Leaf	017-062	24.50
Prunus takesimensis	Stem-bark	016-070	52.74
Pyrus pyrifolia	Leaf	017-034	3.85
Pyrus pyrifolia	Stem-bark	017-035	11.10
Rhamnus davurica	Leaf	017-005	92.35
Rhododendron tschonoskii	Leaf	016-099	9.43
Rhododendron tschonoskii	Stem	016-100	25.70
Rhododendron yedoense var. poukhanense	Stem	016-060	16.80
Rhodotypos scandens	Leaf	017-056	14.20
Rodgersia tabularis	Whole plant	016-005	3.83
Salix hallaisanensis	Stem	016-036	31.12
Sanguisorba hakusanensis	Whole plant	017-068	10.22
Sanguisorba tenuifolia var. alba	Whole plant	017-002	29.37
Sorbus commixta	Stem-bark	016-037	22.84
Sorbus commixta	Leaf	016-038	10.86
Sorbus commixta	Stem	016-039	14.46
Sorbus commixta	fruit	017-039	10.32
Spiraea salicifolia	Leaf	016-016	0.00
Stipa sibirica	Whole plant	017-025	46.66
Suaeda asparagoides	Whole plant	017-026	27.48
Symplocos coreana	Stem	016-067	3.90
Syringa velutina	Leaf	016-093	0.55
Syringa velutina	Stem	016-094	0.35
Tilia insularis	Stem-bark	016-071	10.69
Tripterygium regelii	Stem	017-048	31.59
Ulmus laciniata	Stem-bark	016-022	0.00
Veronica kiusiana	Whole plant	017-028	3.07
Veronica longifolia	Aboveground part	017-022	4.14
Viburnum sargentii	Leaf	017-052	4.31
Vicia amoena	Whole plant	017-006	27.44
Vicia angustifolia var. minor	Whole plant	017-001	17.50
Vicia unijuga	Whole plant	017-027	28.89
Vitex rotundifolia	Leaf	017-075	0.63
Vitis thunbergii var. sinuata	Whole plant	016-014	0.11
Zizyphus jujuba	fruit	017-042	0.00

^aThe degranulation was assessed through the measurement of the release of the granule marker β-hexosaminidase from RBL-2H3 mast cells as described in the “Methods” section. The percent inhibition of degranulation is presented as the mean values from three independent experiments.

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ISSN: 2662-7671

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