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Figure 2 | BMC Complementary and Alternative Medicine

Figure 2

From: Buyang huanwu decoction promotes angiogenesis via vascular endothelial growth factor receptor-2 activation through the PI3K/Akt pathway in a mouse model of intracerebral hemorrhage

Figure 2

BYHWD upregulates pVEGFR2 expression and angiogenesis following ICH. Double-labeling revealed that immunoreactivity for pVEGFR2 (red, arrow) overlapped with vWF+ cells (green, arrow) (A). pVEGFR2-positive microvessels and BrdU+ nuclei (brown, arrow) were shown in vWF+ vessels (blue) in either hemisphere of the sham-operated animals (B and H), ICH group (C and I), SU5416-treated (D and J), BYHWD- treated (E and K) and BYHWD + SU5416-treated (F and L) groups. The immunoreactivity of p-VEGFR2 (G) and the number of BrdU+/vWF+(M) nuclei were compared between BYHWD-treated and non-treated groups.

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