Photomicrograph of cell apoptosis and podocyte marker WT-1 in KK-Aymice kidney. (A) The apoptotic cells were labeled with TUNEL (×400) in mice kidney. (B) The podocytes were perfumed by immunohistochemistry staining of the renal tissues for WT-1 (×400). (C) The average WT-1 positive podocytes per glomerulus were expressed as means ± SEM (n = 40). **P < 0.01 compared to KK-Ay vehicle group.