Effect of AG extract on neuronal damage in MCAO-induced ischemic rats. After MCAO/reperfusion, brain tissues were stained by H&E (A) and Nissl (B). The morphological changes of neuronal cells in a boundary between cortex and penumbra (square box) were observed by a microscope (original magnification ×400). a, sham group; b, vehicle: MCAO-induced ischemic group; c, AG extract at 50 mg/kg-treated group in vehicle; and d, AG extract at 100 mg/kg-treated group in vehicle. The photograph is a representative image of three different tissues.