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Table 5 Urinalyses of animals treated with OJS for 4 weeks

From: Cytotoxicity and sub-acute toxicity in Crl:CD (SD) rats of traditional herbal formula Ojeok-san

Group Volume (mL) Glucosea Bilirubina Ketone bodya Specific gravity Occult blooda pH Urobilinogen (E.U./dL) Colorb
Male          
V. CONTROL 22 ± 4.5 0/5 0/5 0/5 ≤1.005 ~ 1.020 0/5 7.0 0.2 S(5)
500 mg/kg 26 ± 12.4 0/5 0/5 0/5 ≤1.005 ~ 1.020 0/5 7.0 0.2 S(5)
1000 mg/kg 13 ± 2.9 0/5 0/5 0/5 1.015 ~ 1.025 0/5 6.9 0.2 S(5)
2000 mg/kg 22 ± 11.6 0/5 0/5 1/5 1.010 ~ 1.025 0/5 6.8 0.2 S(5)
Female          
V. CONTROL 9 ± 2.0 0/5 0/5 0/5 1.015 ~ 1.025 0/5 6.5 0.2 S(5)
500 mg/kg 9 ± 3.8 0/5 0/5 0/5 1.010 ~ 1.025 0/5 6.8 0.2 S(5)
1000 mg/kg 9 ± 4.5 0/5 1/5 0/5 1.015 ~ 1.025 0/5 6.6 0.2 S(5)
2000 mg/kg 10 ± 4.8 0/5 1/5 0/5 1.010 ~ ≥1.030 0/5 6.5 0.2 S(4), Y(1)
  1. aNumber of animals with sign/Total number of animals observed.
  2. bS, strawberry and Y, yellow.