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Table 5 Urinalyses of animals treated with OJS for 4 weeks

From: Cytotoxicity and sub-acute toxicity in Crl:CD (SD) rats of traditional herbal formula Ojeok-san

Group

Volume (mL)

Glucosea

Bilirubina

Ketone bodya

Specific gravity

Occult blooda

pH

Urobilinogen (E.U./dL)

Colorb

Male

         

V. CONTROL

22 ± 4.5

0/5

0/5

0/5

≤1.005 ~ 1.020

0/5

7.0

0.2

S(5)

500 mg/kg

26 ± 12.4

0/5

0/5

0/5

≤1.005 ~ 1.020

0/5

7.0

0.2

S(5)

1000 mg/kg

13 ± 2.9

0/5

0/5

0/5

1.015 ~ 1.025

0/5

6.9

0.2

S(5)

2000 mg/kg

22 ± 11.6

0/5

0/5

1/5

1.010 ~ 1.025

0/5

6.8

0.2

S(5)

Female

         

V. CONTROL

9 ± 2.0

0/5

0/5

0/5

1.015 ~ 1.025

0/5

6.5

0.2

S(5)

500 mg/kg

9 ± 3.8

0/5

0/5

0/5

1.010 ~ 1.025

0/5

6.8

0.2

S(5)

1000 mg/kg

9 ± 4.5

0/5

1/5

0/5

1.015 ~ 1.025

0/5

6.6

0.2

S(5)

2000 mg/kg

10 ± 4.8

0/5

1/5

0/5

1.010 ~ ≥1.030

0/5

6.5

0.2

S(4), Y(1)

  1. aNumber of animals with sign/Total number of animals observed.
  2. bS, strawberry and Y, yellow.