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Table 2 Relative organ weights rats treated with OJS for 4 weeks

From: Cytotoxicity and sub-acute toxicity in Crl:CD (SD) rats of traditional herbal formula Ojeok-san

Dose (mg/kg/day) 0 500 1000 2000
Male     
Brain 1.966 ± 0.0689 2.036 ± 0.0512 1.922 ± 0.0454 1.975 ± 0.0695
Pituitary gland 0.010 ± 0.0017 0.010 ± 0.0020 0.011 ± 0.0032 0.011 ± 0.0012
Liver 11.204 ± 0.7302 12.838 ± 0.7539 10.520 ± 0.9710 10.789 ± 0.6777
Spleen 0.720 ± 0.0892 0.716 ± 0.0400 0.638 ± 0.0786 0.711 ± 0.1093
Heart 1.225 ± 0.0835 1.138 ± 0.0591 1.096 ± 0.1013 1.194 ± 0.0311
Thymus 0.570 ± 0.0916 0.553 ± 0.1395 0.544 ± 0.0761 0.549 ± 0.1076
Salivary glands 0.604 ± 0.0415 0.572 ± 0.0318 0.548 ± 0.0415 0.605 ± 0.0289
Seminal vesicle 1.124 ± 0.1204 0.956 ± 0.3066 0.890 ± 0.2533 0.986 ± 0.1801
Prostate 0.432 ± 0.0821 0.371 ± 0.0599 0.445 ± 0.0568 0.464 ± 0.0810
Kidneys 2.934 ± 0.2372 3.117 ± 0.1676 2.803 ± 0.2866 2.947 ± 0.2479
Adrenal glands 0.054 ± 0.0069 0.062 ± 0.0098 0.055 ± 0.0022 0.055 ± 0.0079
Testes 3.079 ± 0.1499 3.043 ± 0.1776 2.952 ± 0.1368 2.845 ± 0.5047
Epididymides 0.896 ± 0.0475 0.880 ± 0.0445 0.840 ± 0.0445 0.862 ± 0.1289
Lung 1.357 ± 0.1520 1.473 ± 0.1236 1.322 ± 0.0734 1.377 ± 0.1054
Thyroid/Parathyroid 0.019 ± 0.0038 0.020 ± 0.0034 0.017 ± 0.0028 0.018 ± 0.0023
Female     
Brain 1.851 ± 0.0776 1.840 ± 0.0889 1.815 ± 0.0668 1.833 ± 0.0563
Pituitary gland 0.012 ± 0.0025 0.014 ± 0.0015 0.014 ± 0.0028 0.010 ± 0.0023
Liver 7.367 ± 0.4526 7.096 ± 0.6750 7.435 ± 0.8109 8.006 ± 0.2126
Spleen 0.540 ± 0.0879 0.499 ± 0.0512 0.483 ± 0.0537 0.474 ± 0.0788
Heart 0.807 ± 0.0278 0.762 ± 0.0647 0.820 ± 0.0831 0.833 ± 0.0316
Thymus 0.545 ± 0.1480 0.491 ± 0.0715 0.426 ± 0.0483 0.467 ± 0.0627
Salivary glands 0.412 ± 0.0221 0.387 ± 0.0280 0.403 ± 0.0293 0.410 ± 0.0266
Kidneys 1.807 ± 0.1272 1.877 ± 0.1172 1.930 ± 0.2121 1.885 ± 0.0786
Adrenal glands 0.074 ± 0.0087 0.070 ± 0.0118 0.077 ± 0.0127 0.070 ± 0.0122
Ovaries 0.084 ± 0.0104 0.076 ± 0.0070 0.093 ± 0.149 0.094 ± 0.0171
Lung 1.102 ± 0.0369 1.039 ± 0.0994 1.069 ± 0.1336 1.098 ± 0.0551
Thyroid/parathyroid 0.014 ± 0.0021 0.016 ± 0.0048 0.016 ± 0.0036 0.017 ± 0.0021
Uterus/cervix 0.451 ± 0.1435 0.409 ± 0.1121 0.576 ± 0.1598 0.458 ± 0.0742
  1. Values are presented as mean ± SD.