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Table 2 Relative organ weights rats treated with OJS for 4 weeks

From: Cytotoxicity and sub-acute toxicity in Crl:CD (SD) rats of traditional herbal formula Ojeok-san

Dose (mg/kg/day)

0

500

1000

2000

Male

    

Brain

1.966 ± 0.0689

2.036 ± 0.0512

1.922 ± 0.0454

1.975 ± 0.0695

Pituitary gland

0.010 ± 0.0017

0.010 ± 0.0020

0.011 ± 0.0032

0.011 ± 0.0012

Liver

11.204 ± 0.7302

12.838 ± 0.7539

10.520 ± 0.9710

10.789 ± 0.6777

Spleen

0.720 ± 0.0892

0.716 ± 0.0400

0.638 ± 0.0786

0.711 ± 0.1093

Heart

1.225 ± 0.0835

1.138 ± 0.0591

1.096 ± 0.1013

1.194 ± 0.0311

Thymus

0.570 ± 0.0916

0.553 ± 0.1395

0.544 ± 0.0761

0.549 ± 0.1076

Salivary glands

0.604 ± 0.0415

0.572 ± 0.0318

0.548 ± 0.0415

0.605 ± 0.0289

Seminal vesicle

1.124 ± 0.1204

0.956 ± 0.3066

0.890 ± 0.2533

0.986 ± 0.1801

Prostate

0.432 ± 0.0821

0.371 ± 0.0599

0.445 ± 0.0568

0.464 ± 0.0810

Kidneys

2.934 ± 0.2372

3.117 ± 0.1676

2.803 ± 0.2866

2.947 ± 0.2479

Adrenal glands

0.054 ± 0.0069

0.062 ± 0.0098

0.055 ± 0.0022

0.055 ± 0.0079

Testes

3.079 ± 0.1499

3.043 ± 0.1776

2.952 ± 0.1368

2.845 ± 0.5047

Epididymides

0.896 ± 0.0475

0.880 ± 0.0445

0.840 ± 0.0445

0.862 ± 0.1289

Lung

1.357 ± 0.1520

1.473 ± 0.1236

1.322 ± 0.0734

1.377 ± 0.1054

Thyroid/Parathyroid

0.019 ± 0.0038

0.020 ± 0.0034

0.017 ± 0.0028

0.018 ± 0.0023

Female

    

Brain

1.851 ± 0.0776

1.840 ± 0.0889

1.815 ± 0.0668

1.833 ± 0.0563

Pituitary gland

0.012 ± 0.0025

0.014 ± 0.0015

0.014 ± 0.0028

0.010 ± 0.0023

Liver

7.367 ± 0.4526

7.096 ± 0.6750

7.435 ± 0.8109

8.006 ± 0.2126

Spleen

0.540 ± 0.0879

0.499 ± 0.0512

0.483 ± 0.0537

0.474 ± 0.0788

Heart

0.807 ± 0.0278

0.762 ± 0.0647

0.820 ± 0.0831

0.833 ± 0.0316

Thymus

0.545 ± 0.1480

0.491 ± 0.0715

0.426 ± 0.0483

0.467 ± 0.0627

Salivary glands

0.412 ± 0.0221

0.387 ± 0.0280

0.403 ± 0.0293

0.410 ± 0.0266

Kidneys

1.807 ± 0.1272

1.877 ± 0.1172

1.930 ± 0.2121

1.885 ± 0.0786

Adrenal glands

0.074 ± 0.0087

0.070 ± 0.0118

0.077 ± 0.0127

0.070 ± 0.0122

Ovaries

0.084 ± 0.0104

0.076 ± 0.0070

0.093 ± 0.149

0.094 ± 0.0171

Lung

1.102 ± 0.0369

1.039 ± 0.0994

1.069 ± 0.1336

1.098 ± 0.0551

Thyroid/parathyroid

0.014 ± 0.0021

0.016 ± 0.0048

0.016 ± 0.0036

0.017 ± 0.0021

Uterus/cervix

0.451 ± 0.1435

0.409 ± 0.1121

0.576 ± 0.1598

0.458 ± 0.0742

  1. Values are presented as mean ± SD.