Table 9 Fractional Inhibitory Concentration indices (FICI) of flavonoid/(s) and antibiotics against S. aureus (ATCC 43300) and clinical isolates of MRSA
Flavonoid/(s) + antibiotics | FICI | ||
|---|---|---|---|
|  | S. aureus(ATCC 43300) | MRSA clinical isolates (n = 100) | Inference |
M + R + AMO | 0.9 | 0.9 | Additive |
M + R + CEPH | 0.9 | 0.95 | Additive |
M + R + CET | 0.8 | 0.94 | Additive |
M + R + IMP | 0.84 | 0.85 | Additive |
M + R + ME | 0.95 | 0.97 | Additive |
Q + AMP | 0.74 | 0.77 | Additive |
Q + CEPH | 0.74 | 0.77 | Additive |
Q + CET | 0.66 | 0.69 | Additive |
Q + IMP | 0.66 | 0.69 | Additive |
Q + ME | 0.82 | 0.83 | Additive |
M + R + Q + AMO | 0.59 | 0.66 | Additive |
M + R + Q + AMP | 0.59 | 0.68 | Additive |
M + R + Q + CEPH | 0.46 | 0.50 | Synergism |
M + R + Q + CET | 0.31 | 0.44 | Synergism |
M + R + Q + IMP | 0.32 | 0.45 | Synergism |
M + R + Q + ME | 0.45 | 0.5 | Synergism |