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Table 9 Fractional Inhibitory Concentration indices (FICI) of flavonoid/(s) and antibiotics against S. aureus (ATCC 43300) and clinical isolates of MRSA

From: Antibiotic additive and synergistic action of rutin, morin and quercetin against methicillin resistant Staphylococcus aureus

Flavonoid/(s) + antibiotics FICI
  S. aureus(ATCC 43300) MRSA clinical isolates (n = 100) Inference
M + R + AMO 0.9 0.9 Additive
M + R + CEPH 0.9 0.95 Additive
M + R + CET 0.8 0.94 Additive
M + R + IMP 0.84 0.85 Additive
M + R + ME 0.95 0.97 Additive
Q + AMP 0.74 0.77 Additive
Q + CEPH 0.74 0.77 Additive
Q + CET 0.66 0.69 Additive
Q + IMP 0.66 0.69 Additive
Q + ME 0.82 0.83 Additive
M + R + Q + AMO 0.59 0.66 Additive
M + R + Q + AMP 0.59 0.68 Additive
M + R + Q + CEPH 0.46 0.50 Synergism
M + R + Q + CET 0.31 0.44 Synergism
M + R + Q + IMP 0.32 0.45 Synergism
M + R + Q + ME 0.45 0.5 Synergism