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Table 4 Average zone of inhibitions (in mm ± STDEV) of antibiotics alone and with flavonoid/(s) against S. aureus (ATCC 43300) and MRSA clinical isolates (n =100)

From: Antibiotic additive and synergistic action of rutin, morin and quercetin against methicillin resistant Staphylococcus aureus

 

Antibiotic alone

M + R with antibiotic

Q with antibiotic

M + R + Q with antibiotic

AMO †

0

14.5 ± 0.29

13.5 ± 0.21

23.50 ± 1.1

AMO *

0

14.18 ± 0.36

13.33 ± 0.26

23.73 ± 1.1

AMP †

0

11.5 ± 0.22

17 ± 0.29

22.5 ± 1.2

AMP *

0

11.58 ± 0.21

17.33 ± 0.30

22.63 ± 1.2

CEPH†

0

14.5 ± 0.32

18.5 ± 0.31

24.55 ± 1.00

CEPH*

0

14.18 ± 0.29

18.33 ± 0.30

24.22 ± 1.00

CET †

0

16.5 ± 0.30

20.5 ± 1.00

27 ± 1.20

CET*

0

16.18 ± 0..29

20.83 ± 1.00

27.24 ± 1.23

IMP †

16 ± 0.90

19.5 ± 0.58

22 ± 1.10

28 ± 1.00

IMP*

16.18 ± 0.92

19.62 ± 0.31

22.18 ± 1.12

28.21 ± 0.90

ME †

0

13.5 ± 0.31

16.5 ± 0.28

21.5 ± 1.1

ME*

0

13.18 ± 39

16.89 ± 0.29

21.73 ± 1.0

VAN †

18 ± 0.59

18 ± 0.59

18 ± 0.59

18 ± 0.59

VAN*

17.37 ± 0.80

17.37 ± 0.80

17.37 ± 0.80

17.37 ± 0.80

LEV †

14 ± 0.91

9 ± 0.25

6.5 ± 0.21

3 ± 0.24

LEV*

13.88 ± 1.21

9.52 ± 0.25

6.85 ± 0.22

3.23 ± 0..25

CIP†

10.5 ± 2.5

7.24 ± 0.19

4 ± 0.22

2.25 ± 0.24

CIP*

13.1 ± 3.1

8.1 ± 0.18

4.35 ± 0.24

2.73 ± 0.21

ERY †

22 ± 1.36

22 ± 1.36

22 ± 1.36

22 ± 1.36

ERY*

20.96 ± 2.1

20.96 ± 1.10

20.96 ± 1.10

20.96 ± 1.1

S-T †

0

11.5 ± 0.22

13 ± 0.21

14 ± 0.21

S-T*

0

11.58 ± 0.21

13.33 ± 0.26

14.23 ± 0.26

CEF †

0

11.5 ± 0.22

13 ± 0.21

14 ± 0.21

CEF*

0

11.58 ± 0.21

13.33 ± 0.26

14.23 ± 0.26

  1. † activity against S. aureus (ATCC 43300).
  2. *activity against clinical isolates.