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Table 4 Average zone of inhibitions (in mm ± STDEV) of antibiotics alone and with flavonoid/(s) against S. aureus (ATCC 43300) and MRSA clinical isolates (n =100)

From: Antibiotic additive and synergistic action of rutin, morin and quercetin against methicillin resistant Staphylococcus aureus

  Antibiotic alone M + R with antibiotic Q with antibiotic M + R + Q with antibiotic
AMO † 0 14.5 ± 0.29 13.5 ± 0.21 23.50 ± 1.1
AMO * 0 14.18 ± 0.36 13.33 ± 0.26 23.73 ± 1.1
AMP † 0 11.5 ± 0.22 17 ± 0.29 22.5 ± 1.2
AMP * 0 11.58 ± 0.21 17.33 ± 0.30 22.63 ± 1.2
CEPH† 0 14.5 ± 0.32 18.5 ± 0.31 24.55 ± 1.00
CEPH* 0 14.18 ± 0.29 18.33 ± 0.30 24.22 ± 1.00
CET † 0 16.5 ± 0.30 20.5 ± 1.00 27 ± 1.20
CET* 0 16.18 ± 0..29 20.83 ± 1.00 27.24 ± 1.23
IMP † 16 ± 0.90 19.5 ± 0.58 22 ± 1.10 28 ± 1.00
IMP* 16.18 ± 0.92 19.62 ± 0.31 22.18 ± 1.12 28.21 ± 0.90
ME † 0 13.5 ± 0.31 16.5 ± 0.28 21.5 ± 1.1
ME* 0 13.18 ± 39 16.89 ± 0.29 21.73 ± 1.0
VAN † 18 ± 0.59 18 ± 0.59 18 ± 0.59 18 ± 0.59
VAN* 17.37 ± 0.80 17.37 ± 0.80 17.37 ± 0.80 17.37 ± 0.80
LEV † 14 ± 0.91 9 ± 0.25 6.5 ± 0.21 3 ± 0.24
LEV* 13.88 ± 1.21 9.52 ± 0.25 6.85 ± 0.22 3.23 ± 0..25
CIP† 10.5 ± 2.5 7.24 ± 0.19 4 ± 0.22 2.25 ± 0.24
CIP* 13.1 ± 3.1 8.1 ± 0.18 4.35 ± 0.24 2.73 ± 0.21
ERY † 22 ± 1.36 22 ± 1.36 22 ± 1.36 22 ± 1.36
ERY* 20.96 ± 2.1 20.96 ± 1.10 20.96 ± 1.10 20.96 ± 1.1
S-T † 0 11.5 ± 0.22 13 ± 0.21 14 ± 0.21
S-T* 0 11.58 ± 0.21 13.33 ± 0.26 14.23 ± 0.26
CEF † 0 11.5 ± 0.22 13 ± 0.21 14 ± 0.21
CEF* 0 11.58 ± 0.21 13.33 ± 0.26 14.23 ± 0.26
  1. † activity against S. aureus (ATCC 43300).
  2. *activity against clinical isolates.