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Table 1 Disease activity evaluated by DAS28

From: (5R)-5-Hydroxytriptolide (LLDT-8) inhibits osteoclastogenesis via RANKL/RANK/OPG signaling pathway

Disease activity

The number of cases

Remission

1

Low

0

Moderate

9

High

19

  1. DAS28(ESR) = 0.56*(TJC28) + 0.28*(SJC28) + 0.014*VAS + 0.70*ln(ESR). TJC, means the number of tender joints of 28 counted; SJC, means the number of swollen joints of 28 counted; VAS, the score which scaled out by the subject on 100 mm Visual analog scale to match with joint pain [8]. DAS28 < 2.6, indicated Remission; 2.6 ≤ DAS28 < 3.2, indicated low disease activity; 3.2 ≤ DAS28 ≤ 5.1, indicated moderate disease activity; DAS28 > 5.1, indicated high disease activity [9].