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Table 4 IC 50 values of extract and fractions of N. jatamansi and doxorubicin in ER (+) MCF-7 and ER (−) MDA-MB-231 human breast carcinoma cells

From: Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinoma

Extract/fraction

IC50(μg/mL)

MCF-7

MDA-MB-231

NJM

58.01 ± 6.13a,g

23.83 ± 0.69a,g

NJPE

60.59 ± 4.78a,d

38.25 ± 2.17a,e

NJDE

69.94 ± 3.92a,d,e,h

25.04 ± 0.90a,e,f,h

NJEA

65.44 ± 4.63a,d,e

40.72 ± 5.22b,e,f

NJAQ

141.35 ± 13.35b

117.13 ± 6.29c

Doxorubicin

2.20 ± 0.30c

0.31 ± 0.09d

  1. All the values are expressed as mean ± SEM (n = 3). a-fColumn wise values with different superscripts of this type indicate significant difference (P < 0.05).
  2. g-hRow wise values with different superscripts of this type indicate significant difference (P < 0.05).
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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