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Table 7 Effect of leaf extract of P. hydropiper extract on involvement of cyclic guanosine monophosphate (cGMP) pathway

From: Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice

Treatment Dose (mg/kg) Number of writhing Inhibition (%)
Control 0.1 ml/mouse 59.1 ± 1.86 -
Methylene Blue (MB) 20 52.8 ± 3.15 10.66
MEPH + MB 25 + 20 6.9 ± 0.73* 88.32
MEPH + MB 50 + 20 5.8 ± 1.88* 90.19
MEPH + MB 75 + 20 5.3 ± 3.85* 91.03
  1. Each value is presented as the Mean ± SEM (n = 5). MEPH = Methanolic extract of P. hydropiper leaves.
  2. *p < 0.001 compared with the control group (Dunnett’s test).