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Table 4 Effect of leaf extract of P. hydropiper extract in formalin-induced nociception

From: Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice

Treatment

Dose (mg/kg)

Licking of the hind paw

Early phase (0-5 min)

Inhibition (%)

Late phase (15-30 min)

Inhibition (%)

Control

0.1 ml/mouse

114.6 ± 9.88

-

46.8 ± 5.66

-

Diclofenac sodium

10

22.4 ± 1.83*

80.45

1.4 ± 0.97*

97.00

MEPH

25

69.2 ± 3.61*

39.61

2.4 ± 1.15*

86.75

MEPH

50

46.8 ± 2.69*

59.16

1 ± 0.92*

90.17

MEPH

75

31 ± 3.42*

72.94

2.8 ± 0.86*

94.017

  1. Each value is presented as the Mean ± SEM (n = 5). MEPH = Methanolic extract of P. hydropiper leaves.
  2. *p < 0.001 compared with the control group (Dunnett’s test).