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Table 4 Effect of leaf extract of P. hydropiper extract in formalin-induced nociception

From: Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice

Treatment Dose (mg/kg) Licking of the hind paw
Early phase (0-5 min) Inhibition (%) Late phase (15-30 min) Inhibition (%)
Control 0.1 ml/mouse 114.6 ± 9.88 - 46.8 ± 5.66 -
Diclofenac sodium 10 22.4 ± 1.83* 80.45 1.4 ± 0.97* 97.00
MEPH 25 69.2 ± 3.61* 39.61 2.4 ± 1.15* 86.75
MEPH 50 46.8 ± 2.69* 59.16 1 ± 0.92* 90.17
MEPH 75 31 ± 3.42* 72.94 2.8 ± 0.86* 94.017
  1. Each value is presented as the Mean ± SEM (n = 5). MEPH = Methanolic extract of P. hydropiper leaves.
  2. *p < 0.001 compared with the control group (Dunnett’s test).