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Table 2 Inhibitory effects of the TAFU on the tumor growth of S180 and LLC tumor models

From: Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action

Groups

Dose (mg/kg)

No. of animals

Weight of tumor (g)

Inhibition (%)

S180 tumor model

Control

-

10

1.20 ± 0.30

-

TAFU

20

10

1.22 ± 0.21

−1.46

 

40

10

0.99 ± 0.10*

17.80

 

80

10

0.62 ± 0.06**

48.56

CTX

20

10

0.53 ± 0.13***

55.92

LLC tumor model

Control

-

10

2.27 ± 0.16

-

TAFU

20

10

2.38 ± 0.17

−4.68

 

40

10

2.11 ± 0.24

7.22

 

80

10

1.36 ± 0.20**

39.96

CTX

20

10

0.94 ± 0.11***

58.37

  1. The reported values are the means ± S.E.M. (n = 10). Significant differences compared to Control group are indicated by *P < 0.05, **P < 0.01 and ***P < 0.001.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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