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Table 2 Hypoglycemic effects O . interifolia 80% methanolic leaf extract on fasting blood glucose levels in normoglycemic mice

From: Methanolic leaf exctract of Otostegia integrifolia Benth reduces blood glucose levels in diabetic, glucose loaded and normal rodents

Blood glucose levels (mg/dl)

Groups

0 h

1 h

2 h

3 h

4 h

TW80

92.50 ± 1.05

87.66 ± 2.51

84.77 ± 3.85

83.11 ± 2.72

83.27 ± 4.26

GL5

90.83 ± 4.87

59.16 ± 3.41a2b3c1d3e3

61.38 ± 2.72a2d1e3

57.66 ± 3.12a3d3e3f3

48.50 ± 1.59a3d3e3f3

OI 100

89.66 ± 6.44

97.58 ± 3.81e3

78.50 ± 6.15e3

66.16 ± 2.85a1d1e3

57.66 ± 3.87a3d3e3f3

OI 200

94.75 ± 5.11

80.3 ± 3 7.09e3

64.08 ± 4.38a1e3

55.75 ± 2.65a3d3e3f3

49.50 ± 1.24a3d3e3f3

OI 400

99.58 ± 5.90

89.25 ± 6.25

82.66 ± 5.26

85.08 ± 6.00

84.75 ± 5.59

  1. Values are mean ± SEM. n = 6; acompared to TW80; bcompared to OI 100; ccompared to OI 200; dcompared to OI 400; ecompared to 0 h: fcompared to 1 h. 1p < 0.05; 2p < 0.01; 3p < 0.001. (TW80, control that received Tween80; GL5, positive control received glibenclamide 5 mg/kg: OI 100, extract 100 mg/kg; OI 200, extract 200 mg/kg; OI 400, extract 400 mg/kg).