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Table 1 Antidiabetic effects O . interifolia 80% methanolic leaf extract on fasting blood glucose levels in streptozotocin induced mice

From: Methanolic leaf exctract of Otostegia integrifolia Benth reduces blood glucose levels in diabetic, glucose loaded and normal rodents

Blood glucose levels (mg/dl)

Groups

0 h

1 h

2 h

3 h

4 h

TW80

347.61 ± 41.81

362.83 ± 43.81

402.55 ± 22.67

402.22 ± 26.51

375.50 ± 23.71

GL5

337.22 ± 33.32

304.94 ± 36.03

217.33 ± 17.10b2

166.16 ± 13.27a3b3c2

139.38 ± 12.00a3b3c3

OI 100

424.58 ± 59.47

407.66 ± 63.11

350.08 ± 67.63

279.08 ± 60.26

191.83 ± 45.53a3

OI 200

396.25 ± 57.88

364.08 ± 60.11

318.41 ± 60.98

243.33 ± 63.24

159.83 ± 71.10a3b1

OI 400

386.66 ± 57.13

312.00 ± 54.82

270.33 ± 61.98

228.41 ± 51.48

207.00 ± 44.25

  1. Values are mean ± SEM. n = 6; acompared to TW80; bcompared to 0 h ccompared to 1 h. 1p < 0.05; 2p < 0.01; 3p < 0.001. (TW80, control that received Tween80; GL5, positive control received glibenclamide 5 mg/kg: OI 100, extract 100 mg/kg; OI 200, extract 200 mg/kg; OI 400, extract 400 mg/kg).