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Table 2 Anti-proliferative activity (IC 50 values) of the most active subfractions from the ethyl acetate fraction on selected cancer cell lines

From: In vitro anti-proliferative activity of Argemone gracilenta and identification of some active components

Cancer cell line

IC50(μg/mL)

FAg-4A

FAg-5B

FAg-7A

FAg-7B

M12.C3F6

16.81 ± 4.0b

24.9 ± 2.2a

2.8 ± 0.3c

2.4 ± 0.4c

RAW 264.7

34.1 ± 5.8b

35.4 ± 10.14b

2.5 ± 0.5b

2.7 ± 0.1b

HeLa

91.8 ± 7.6a

67.61 ± 5.6c

12.1 ± 1.7d

79.5 ± 11.5b

L-929

151.7 ± 1.5a

85.1 ± 2.3b

> 100*

> 100*

  1. Data are shown as the mean ± SD from three independent repeats after a 48-h exposure to the test subfractions. Significant differences (p < 0.05) are indicated by different letters (a-d). The asterisk (*) represents the maximum concentration tested that did not reach IC50 values.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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