BMC Complementary Medicine and Therapies

Table 1 Anti-proliferative activity (IC ₅₀ values) of the methanol extract and fractions of Argemone gracilenta on selected cancer cell lines

From: In vitro anti-proliferative activity of Argemone gracilenta and identification of some active components

Cancer cell line	IC₅₀(μg/mL)
Cancer cell line	Methanol	Hexane	Ethyl acetate	Ethanol	Residual
M12.C3F6	46.20 ± 8.41ª	20.40 ± 2.30^c	32.60 ± 1.10^b	21.08 ± 0.84^c	40.60 ± 10.08^a
RAW 264.7	64.45 ± 8.97ª	36.06 ± 6.55^d	41.27 ± 4.27^c	55.18 ± 8.80^b	64.65 ± 5.36ª
HeLa	78.87 ± 8.52^b	70.62 ± 5.80^c	126.28 ± 5.73ª	> 200*	> 200*
L-929	160.60 ± 2.15^b	131.30 ± 3.39^c	180.61 ± 4.37ª	> 200*	> 200*

Data are shown as the mean ± SD from three independent repeats after a 48-h exposure to the test extract and fractions. Significant differences (p < 0.05) are indicated by different letters (a-d). The asterisk (*) represents the maximum concentration tested that did not reach IC₅₀ values.

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ISSN: 2662-7671

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