Skip to main content
Figure 2 | BMC Complementary and Alternative Medicine

Figure 2

From: Arthropod steroid hormone (20-Hydroxyecdysone) suppresses IL-1β- induced catabolic gene expression in cartilage

Figure 2

Regulatory mechanisms of Epas1 expression in articular cartilage explants under IL-1β treatment. In this study, mouse articular cartilage explants are treated with IL-1β cytokines. The results showed that IL-1β can enhance Epas1 gene expression (A), and suppress collagen type II (Col2a1) gene expression (B). The pretreatment of 10−8M Ecd can effectively eliminate the Epas1 gene expression enhanced by IL-1β treatment. (Each value is the mean ± standard deviations; n = 8; *:p<0.05; **:p< 0.01; ***:p < 0.001).

Back to article page