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Table 1 Biochemical markers of tissue and organ injury in mice subjected to heatstroke

From: Xuebijing injection reduces organ injuries and improves survival by attenuating inflammatory responses and endothelial injury in heatstroke mice

 

Sham

HS

HSXBJ

ALT (U/L)

27.0 ± 4.2

283.3 ± 37.9***

71.3 ± 10.2###

AST (U/L)

21.5 ± 5.4

426.3 ± 47.1***

162.5 ± 24.0###

Cr (μmol/L)

32.8 ± 6.0

172.0 ± 17.7***

116.3 ± 11.5#

BUN (mmol/L)

2.9 ± 0.6

18.7 ± 1.4***

13.2 ± 1.1##

LDH (U/L)

81.0 ± 9.6

439.0 ± 62.7***

165.3 ± 22.2###

Tn (μg/L)

0.12 ± 0.02

4.08 ± 0.59***

1.65 ± 0.31##

  1. Mice pretreated with 4 ml/kg of XBJ (HSXBJ group) or 0.9% saline (HS group) were subjected to heat insults. Values represents mean ± SE. ALT, alanine aminotransferase; AST, aspartic aminotransferase; Cr creatinine; BUN, blood urea nitrogen, LDH, lactate dehydrogenase; Tn, troponin. ***P < 0.001, vs. sham group; #P < 0.05, ##P < 0.01, ###P < 0.001, vs. HS group.