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Table 4 IC50 values (μg/ml) for cell growth inhibition of the investigated methanolic extracts on three human cancer cell lines and phytochemical screening.

From: Studies of the in vitro anticancer, antimicrobial and antioxidant potentials of selected Yemeni medicinal plants from the island Soqotra

Plant species Extracts Cell lines Phytochemical screening
   5637 MCF-7 A-427  
Acacia pennivenia Methanolic > 50 > 50 > 50 Saponins, tannins
Acanthospermum hispidum Methanolic 9.37 ± 1.98 19.92 ± 8.94 16.70 ± 2.32 Sesquiterpene lactones
Acridocarpus socotranus Methanolic > 50 > 50 > 50 Flavonoids, terpenoids
Aloe perryi Methanolic > 50 > 50 > 50 Anthraquinons, flavonoids
Ballochia atro-virgata Methanolic 2.83 ± 2.06 2.94 ± 0.28 1.58 ± 0.54 Terpenoids
Blepharis spiculifolia Methanolic > 50 > 50 > 50 Phenolic compounds, terpenoids
Boswellia dioscorides Methanolic 29.0 ± 8.26 > 50 27.60 ± 10.31 Volatile oil, terpenoids, flavonoids
Boswellia socotrana Methanolic 18.4 ± 4.66 > 50 24.9 ± 8.73 Volatile oil, terpenoids, flavonoids
Capparis cartilaginea Methanolic > 50 > 50 > 50 Glucosinolates, flavonoids
Commiphora ornifolia Methanolic 30.2 ± 3.12 38.5 ± 1.93 35.1 ± 3.15 Volatile oil, terpenoids, flavonoids
Corchorus erodioides Methanolic > 50 > 50 > 50 Flavonoids, phenolic compounds
Croton socotranus Methanolic > 50 > 50 > 50 Flavonoids, terpenoids, tannins
Euclea divinorum Methanolic > 50 > 50 > 50 Phenolic acids, tannins
Euphorbia socotrana Methanolic 42.0 ± 7.43 > 50 38.1 ± 13.49 Terpenoids, flavonoids, steroids, tannins
Eureiandra balfourii Methanolic 0.82 ± 0.15 3.47 ± 1.18 2.25 ± 0.57 Trepenoids, flavonoids
Ficus cordata Methanolic > 50 > 50 > 50 Tannins, terpenoids
Glossonema revoili Methanolic > 50 > 50 > 50 Steroids, flavonoids
Hibiscus noli-tangere Methanolic > 50 > 50 > 50 Tannins, lignans
Hypoestes pubescens Methanolic 8.25 ± 3.49 7.03 ± 2.02 4.85 ± 1.70 Alkaloids, terpenoids
Lannea transulta Methanolic > 50 > 50 > 50 Tannins, flavonoids
Leucas samhaensis Methanolic > 50 > 50 > 50 Volatile oil, terpenoids and flavonoids
Leucas virgata Methanolic > 50 > 50 > 50 Volatile oil, terpenoids and flavonoids
Lycium sokotranum Methanolic > 50 > 50 > 50 Alkaloids
Maerua angolensis Methanolic > 50 > 50 > 50 Glucosinolates, tannins
Rhus thyrsiflora Methanolic > 50 > 50 > 50 Flavonoids, terpenoids, tannins
Teucrium sokotranum Methanolic > 50 > 50 > 50 Volatile oil, terpenoids
Etoposide (μM)   0.54 ± 0.30 0.50 ± 0.19 0.13 ± 0.10  
  1. Values are averages and standard deviations of three or more independent determinations.