Table 4 IC50 values (μg/ml) for cell growth inhibition of the investigated methanolic extracts on three human cancer cell lines and phytochemical screening.
Plant species | Extracts | Cell lines | Phytochemical screening | ||
|---|---|---|---|---|---|
| Â | Â | 5637 | MCF-7 | A-427 | Â |
Acacia pennivenia | Methanolic | > 50 | > 50 | > 50 | Saponins, tannins |
Acanthospermum hispidum | Methanolic | 9.37 ± 1.98 | 19.92 ± 8.94 | 16.70 ± 2.32 | Sesquiterpene lactones |
Acridocarpus socotranus | Methanolic | > 50 | > 50 | > 50 | Flavonoids, terpenoids |
Aloe perryi | Methanolic | > 50 | > 50 | > 50 | Anthraquinons, flavonoids |
Ballochia atro-virgata | Methanolic | 2.83 ± 2.06 | 2.94 ± 0.28 | 1.58 ± 0.54 | Terpenoids |
Blepharis spiculifolia | Methanolic | > 50 | > 50 | > 50 | Phenolic compounds, terpenoids |
Boswellia dioscorides | Methanolic | 29.0 ± 8.26 | > 50 | 27.60 ± 10.31 | Volatile oil, terpenoids, flavonoids |
Boswellia socotrana | Methanolic | 18.4 ± 4.66 | > 50 | 24.9 ± 8.73 | Volatile oil, terpenoids, flavonoids |
Capparis cartilaginea | Methanolic | > 50 | > 50 | > 50 | Glucosinolates, flavonoids |
Commiphora ornifolia | Methanolic | 30.2 ± 3.12 | 38.5 ± 1.93 | 35.1 ± 3.15 | Volatile oil, terpenoids, flavonoids |
Corchorus erodioides | Methanolic | > 50 | > 50 | > 50 | Flavonoids, phenolic compounds |
Croton socotranus | Methanolic | > 50 | > 50 | > 50 | Flavonoids, terpenoids, tannins |
Euclea divinorum | Methanolic | > 50 | > 50 | > 50 | Phenolic acids, tannins |
Euphorbia socotrana | Methanolic | 42.0 ± 7.43 | > 50 | 38.1 ± 13.49 | Terpenoids, flavonoids, steroids, tannins |
Eureiandra balfourii | Methanolic | 0.82 ± 0.15 | 3.47 ± 1.18 | 2.25 ± 0.57 | Trepenoids, flavonoids |
Ficus cordata | Methanolic | > 50 | > 50 | > 50 | Tannins, terpenoids |
Glossonema revoili | Methanolic | > 50 | > 50 | > 50 | Steroids, flavonoids |
Hibiscus noli-tangere | Methanolic | > 50 | > 50 | > 50 | Tannins, lignans |
Hypoestes pubescens | Methanolic | 8.25 ± 3.49 | 7.03 ± 2.02 | 4.85 ± 1.70 | Alkaloids, terpenoids |
Lannea transulta | Methanolic | > 50 | > 50 | > 50 | Tannins, flavonoids |
Leucas samhaensis | Methanolic | > 50 | > 50 | > 50 | Volatile oil, terpenoids and flavonoids |
Leucas virgata | Methanolic | > 50 | > 50 | > 50 | Volatile oil, terpenoids and flavonoids |
Lycium sokotranum | Methanolic | > 50 | > 50 | > 50 | Alkaloids |
Maerua angolensis | Methanolic | > 50 | > 50 | > 50 | Glucosinolates, tannins |
Rhus thyrsiflora | Methanolic | > 50 | > 50 | > 50 | Flavonoids, terpenoids, tannins |
Teucrium sokotranum | Methanolic | > 50 | > 50 | > 50 | Volatile oil, terpenoids |
Etoposide (μM) |  | 0.54 ± 0.30 | 0.50 ± 0.19 | 0.13 ± 0.10 |  |