Figure 8
Hypothetical diagram of the mechanism through which Congaplex ® and Immuplex ® affect T lymphocyte function. Top Congaplex® and Immuplex® regulated the PHA/PMA-induced expression of RNA corresponding to cytokines resulting in an increase or decrease, respectively, of cytokine concentrations in the media Bottom Congaplex® and Immuplex® decreased the production of IFN-γ, the predominant Th1-specific cytokine detected in the media, and increased the production of IL-13, the predominant Th2-specific cytokine present in the media, in response to PHA.