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Table 3 Summary of the interaction of the plant extract and the various antibiotics

From: Justification for the use of Ocimum gratissimum L in herbal medicine and its interaction with disc antibiotics

Test isolates

Antibiotic

Antibiotic alone (mm)

Antibiotic plus plant extract (mm)

% change in IZD

Interpretation

S. aureus

CP

16

16

0

indifference

 

SX

15

15

0

indifference

 

PN

-

-

-

-

 

SE

24

22

-8.33

antagonism

P. aeruginosa

CP

29

35

20.69

synergism

 

SX

23

12

-47.83

antagonism

 

PN

-

-

-

-

 

SE

29

-

-

-

P. mirabilis

CP

15

25

66.67

synergism

 

SX

24

26

8.33

additive

 

PN

12

20

66.67

synergism

 

SE

29

19

-34.48

antagonism

E. coli

CP

35

42

20

synergism

ATCC 11775

SX

10

12

20

synergism

 

PN

16

10

-37.5

antagonism

 

SE

22

11

-50

antagonism

E. coli

CP

39

40

2.56

additive

 

SX

10

12

20

synergism

 

PN

8

10

25

synergism

 

SE

14

11

-21.42

antagonism

C. albicans

KE

26

23

-11.54

antagonism

ATCC 90028

NY

38

30

-7.14

antagonism

C. albicans

KE

21

27

28.57

synergism

 

NY

24

32

33.33

synergism

  1. Key: -, No activity; CP, 10 mg of ciprofloxacin; SX, 30 mg of septrin; SE, 30 mg of streptomycin; PN, 30 mg of ampicillin; KE, ketoconazole; NY, nystatin.; %, percentage; IZD, inhibition zone diameter.