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Table 3 Summary of the interaction of the plant extract and the various antibiotics

From: Justification for the use of Ocimum gratissimum L in herbal medicine and its interaction with disc antibiotics

Test isolates Antibiotic Antibiotic alone (mm) Antibiotic plus plant extract (mm) % change in IZD Interpretation
S. aureus CP 16 16 0 indifference
  SX 15 15 0 indifference
  PN - - - -
  SE 24 22 -8.33 antagonism
P. aeruginosa CP 29 35 20.69 synergism
  SX 23 12 -47.83 antagonism
  PN - - - -
  SE 29 - - -
P. mirabilis CP 15 25 66.67 synergism
  SX 24 26 8.33 additive
  PN 12 20 66.67 synergism
  SE 29 19 -34.48 antagonism
E. coli CP 35 42 20 synergism
ATCC 11775 SX 10 12 20 synergism
  PN 16 10 -37.5 antagonism
  SE 22 11 -50 antagonism
E. coli CP 39 40 2.56 additive
  SX 10 12 20 synergism
  PN 8 10 25 synergism
  SE 14 11 -21.42 antagonism
C. albicans KE 26 23 -11.54 antagonism
ATCC 90028 NY 38 30 -7.14 antagonism
C. albicans KE 21 27 28.57 synergism
  NY 24 32 33.33 synergism
  1. Key: -, No activity; CP, 10 mg of ciprofloxacin; SX, 30 mg of septrin; SE, 30 mg of streptomycin; PN, 30 mg of ampicillin; KE, ketoconazole; NY, nystatin.; %, percentage; IZD, inhibition zone diameter.