Anti-Inflammatory properties of Salograviolide A purified from Lebanese plant Centaurea ainetensis

Table 1 Effect of SA on reversing inflammation in the in-vivo IBD model

Treatment	Tissues Removed at 6 h After Treatment^a	Tissues Removed at 24 h After Treatment^a
Control (no treatment)	0	0
Treatment with SA (12 mg/kg, i.p. injection)	0	0
Rats treated with ethanol	0	0
Rats treated with methyl cellulose	0	0
Rats treated with iodoacetoamide (representing inflamed tissue)	2	3^b
Rats treated twice with SA prior to iodoacetoamide	1.0	1.0^c

^a Inflammation score
^b P < 0.005, ^b represents the comparison of iodoacetoamide treatment on inflammation score as compared to untreated control. Data are means of 3 separate experiments.
^c P < 0.005, ^c represents the comparison of SA pretreatment on iodoacetoamide treated rats as compared to iodoacetoamide treated rats. Data are means of 3 separate experiments.

ISSN: 2662-7671