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Table 3 Secondary outcomes

From: Acupuncture in acute herpes zoster pain therapy (ACUZoster) – design and protocol of a randomised controlled trial

→ Variation of the primary outcome (averaged pain intensity)
→ Frequency of pain attacks per day
→ Pain intensity:
   ▪ Pain at rest
   ▪ Pain attack
→ Time to symptom alleviation
→ Analgesic demand
→ Side effects of the therapy
→ Standardised pain questionnaires
   ▪ Neuropathic Pain questionnaire (NPI)
   ▪ Quality of life (SF 36)
   ▪ Pain Disability Index (PDI)
   ▪ Pain description acc. to Geissner (SES)
   ▪ Pain discomfort list acc. to van Zerssen
→ Quantitative sensory testing (QST):
   ▪ thermic sensation:
▪ cold and warm detection threshold (CDT + WDT)
▪ thermic difference threshold (TSL)
▪ cold and heat pain threshold (CPT + HPT)
   ▪ tactile detection threshold
   ▪ mechanical pain threshold
   ▪ mechanical pain intensity
   ▪ mechanical allodynia
   ▪ wind up phenomenon
   ▪ vibration threshold
   ▪ pressure pain threshold
→ Change of rash before and after treatment
→ Incidence of postherpetic neuralgia 6 month after treatment
→ Credibility
→ Cost effectiveness
→ Side effects