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Table 2 Effect and side effects in the two groups.

From: Alternative vs. conventional treatment given on-demand for gastroesophageal reflux disease: a randomised controlled trial

Effect and side effects

Eso20

PRA

Statistics

Overall satisfaction with the treatment (no)

36 (92%)

22 (58%)

p = 0.001

Weeks of satisfactory relief (mean proportion)

89% (26)

62% (44)

p = 0.008

Symptom score at the end of treatment (mean)

5.9 (3.4)

8.0 (4.4)

p = 0.019

Preference for same drug after the trial (no)

33 (85%)

16 (42%)

P < 0.001

Preference for regular treatment (no)

6 (15%)

6 (16%)

ns (p = 1.00)

Diarrhoea (no)

1 (3%)

6 (16%)

ns (p = 0.056)

Too many tablets (no)

2 (6%)

11 (29%)

p = 0.006

Delayed onset of effect (no)

10 (26%)

4 (11%)

ns (p = 0.14)

Rapid relapse of symptoms (no)

8 (21%)

18 (47%)

p = 0.017

  1. The results are given as number of patients (proportion in brackets) or mean (standard deviation in brackets).
  2. Eso20: Esomeprazole 20 mg.
  3. PRA: Pectin-based Raft-forming Agent.