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Table 1 General animal characteristics parameters in the control group and in rats treated with MCT (i.p; Heart failure) or with MCT + C. Dactylon rhizomes hydroalcoholic extract (orally).

From: Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats

Parameter

Untreated

Treated with Digoxin

Treated with C. dactylon extract

 

Control

MCT

0.01 mg/kg

50 mg/kg

100 mg/kg

200 mg/kg

Baseline BW (g)

151 ± 12

150 ± 10

144 ± 9

147 ± 11

143 ± 9

152 ± 13

Δ BW (g)

57 ± 6

26 ± 9†

38 ± 11*

32 ± 9

40 ± 6*

43 ± 11**

Ventricles Wet to Dry weight ratio

4.35 ± 0.3

5.0 ± 0.13†

4.64 ± 0.3*

4.61 ± 0.26*

4.50 ± 0.27**

4.52 ± 0.25**

Wet ventricle weight to Body weight ratio (g/kg)

3.31 ± 0.3

4.9 ± 0.7†

4.6 ± 0.7

4.9 ± 1.3

4.2 ± 0.8

3.25 ± 0.3**

Lung Wet to Dry weight ratio

3.98 ± 0.18

4.98 ± 0.41†

4.76 ± 0.21

4.69 ± 0.41

4.70 ± 0.22

4.46 ± 0.25**

Wet Lung weight to Body weight ratio (g/kg)

5.01 ± 0.83

8.90 ± 2.9†

10.82 ± 2.9

10.03 ± 2.9

8.33 ± 3.4

4.78 ± 0.87**

Mortality (%)

0

20

40

20

20

10

  1. Data is expressed as mean ± SD.
  2. Baseline BW, body weights immediately prior to extract administration; Δ BW, increase in body weight over 2-weeks treatment period. All other values obtained 4 weeks after MCT administration. Treatments were started 2 weeks after MCT administration and continued for 2 weeks. † p < 0.01 from respective control value; *p < 0.05; **p < 0.01 from MCT treated group using one way ANOVA.