Figure 4
From: Anti-tumor effect of Liqi, a traditional Chinese medicine prescription, in tumor bearing mice
Effect of Liqi on NK cell cytotoxicity in tumor-bearing mice. Sarcoma 180 tumor cells were subcutaneously implanted (2 × 106cells suspended in 50 μl of PBS) in the right axillary region of syngeneic BALB/c mice. After 24 h, liqi (50 g/kg) was administrated daily by gavage for 12 days. NK cell cytotoxicity was tested using YAC-1 cells as target cells. LDH in culture supernatants was determined using the LDH Cytotox assay kit according to the manufacturer's instructions. Results are expressed as the mean ± S.D. of 12 mice. *P < 0.05, compared with untreated control of tumor-transplanted animals (model group). The normal group indicates healthy animals without tumor xenograft for comparison.