Effect of Pt in HUVEC migration capacity evaluated by double chamber assay. Incubation with 8 μM Pt resulted in decreased cell invasion. Bars represent the percentage of invading cells relative to the initial amount of cells cultured. Results are expressed as percentage of control cells. Assays were repeated five times and performed in triplicate. Statistical differences between groups were evaluated by one-way analysis of variance (ANOVA test) followed by the Dunnet test. *p < 0.01 vs. Control.