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Table 1 Effect of HCE prophylactic treatment on peritoneal cell activation and local and systemic inflammatory mediators in mice submitted to the CLP

From: Syzygium jambolanum treatment improves survival in lethal sepsis induced in mice

  Control HCE 5 HCE 50
Spreading index (%) 13.1 ± 2.0a 17.3 ± 3.3* 36.2 ± 3.1*
Spontaneous H2O2 release (μM) 10.4 ± 0.1 17.2 ± 0.2* 19.2 ± 0.2*
Nitrite in the culture supernatant (μM) 5.4 ± 0.7 6.3 ± 0.5 7.6 ± 0.5
Seric Nitrite (μM) 165.1 ± 2.5 155.3 ± 3.1* 127.7 ± 2.3*
Seric TNF (UL/mL) 4.0 ± 1.1 2.5 ± 0.5* 0.5 ± 0.2*
  1. aThe results were expressed as mean ± S.E.M (10 animals/group).
  2. *p < 0.05 when compared to the control group.