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Table 1 Effect of HCE prophylactic treatment on peritoneal cell activation and local and systemic inflammatory mediators in mice submitted to the CLP

From: Syzygium jambolanum treatment improves survival in lethal sepsis induced in mice

 

Control

HCE 5

HCE 50

Spreading index (%)

13.1 ± 2.0a

17.3 ± 3.3*

36.2 ± 3.1*

Spontaneous H2O2 release (μM)

10.4 ± 0.1

17.2 ± 0.2*

19.2 ± 0.2*

Nitrite in the culture supernatant (μM)

5.4 ± 0.7

6.3 ± 0.5

7.6 ± 0.5

Seric Nitrite (μM)

165.1 ± 2.5

155.3 ± 3.1*

127.7 ± 2.3*

Seric TNF (UL/mL)

4.0 ± 1.1

2.5 ± 0.5*

0.5 ± 0.2*

  1. aThe results were expressed as mean ± S.E.M (10 animals/group).
  2. *p < 0.05 when compared to the control group.