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Figure 5 | BMC Complementary and Alternative Medicine

Figure 5

From: Neuroprotective efficacy and therapeutic window of curcuma oil: in rat embolic stroke model

Figure 5

Brain tissue Nitrate/Nitrite levels were estimated at 6, 12 and 24 hrs after ischemia. Rats from sham-operated, peanut oil treated ischemic and C.oil treated groups were euthanized at 6, 12 and 24 hrs. At each time point five rats/group were used for the study. Data are expressed as mean ± S.E.M P < 0.001 was considered significant when comparisons were made with the peanut oil treated ischemic group by one way ANOVA followed by Newman Keuls post hoc test.(a): Nitrate levels and (b): Nitrite levels. (c): Effect of C.oil on myeloperoxidase (MPO) activity after 24 hrs of ischemia. Five rats per group from sham-operated, peanut oil treated ischemic and C.oil post treated were euthanized at 24 hrs Data are expressed as mean fluorescence ± S.E.M. Statistical significance was assessed by one way ANOVA. P < 0.001 was considered highly significant when comparisons were made between the peanut oil treated ischemic and the C.oil post-treatment group by Newman Keuls post hoc test. Neuroprotective effect of brain tissue caspase-3 (d): and caspase 1&4 (e): activity after 24 hrs of ischemia. Five rats each group from sham-operated, peanut oil treated ischemic and the treatment group with C.oil were euthanized at 24 hrs. Data are expressed as mean fluorescence ± S.E.M. Statistical significance was assessed by one way ANOVA. P < 0.05 was considered significant when comparisons were made among different groups by Newman Keuls post hoc test.

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