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Table 3 The effect of PK, Omez, and indomethacin as such and in combination with PK or Omez on the gastric secretion of pylorous ligated mice.a

From: Healing Potential of Picrorhiza kurroa (Scrofulariaceae) rhizomes against indomethacin-induced gastric ulceration: a mechanistic exploration.

Mice Gastric juice (ml) (6 h) pH Acid output (μEq/6 h)
Experimental control 0.85 ± 0.1 3.56 183.6 ± 6.8
Treated with PK 0.7 ± 0.1 3.41 179.2 ± 4.6
Treated with indomethacin 1.6 ± 0.2b 2.3 256.6 ± 10.2a
Treated with PK + indomethacin 1.3 ± 0.1c 3.46 206.2 ± 5.9c
Treated with Omez 0.75 ± 0.09 3.36 186.5 ± 6.8c
Treated with Omez + indomethacin 0.9 ± 0.12d 3.25 173.6 ± 6.4c
  1. aUntreated and treated mice were subjected to pylorous ligation. The treatment groups were orally administered PK (20 mg/kg/day × 3 days), Omez (3 mg/kg/day × 3 days), indomethacin (18 mg/kg × 1 d) as such or along with PK and Omez at the designated doses. The values are mean ± SEM (n = 5). a P < 0.05, b P < 0.01 compared to the experimental control mice c P < 0.05, d P < 0.01 compared to the indomethacin-treated mice