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Table 2 The effect of PK and Omez on the levels of TBARS, protein carbonyls, non-protein thiol, and mucin in the ulcerated gastric tissue of micea on day three of ulceration

From: Healing Potential of Picrorhiza kurroa (Scrofulariaceae) rhizomes against indomethacin-induced gastric ulceration: a mechanistic exploration.

Parameters Group I normal control Group III 3rd day ulcerated control Group V PK-treated Group VI Omez-treated
TBARS (nmoles/mg protein) 1.02 ± 0.06 1.53 ± 0.06c 1.03 ± 0.09d 1.08 ± 0.05d
Protein carbonyls (nmoles/mg protein) 1.18 ± 0.07 2.61 ± 0.17c 1.62 ± 0.10f 1.59 ± 0.09f
NP-TSH (nmoles/mg tissue) 2.06 ± 0.09 1.73 ± 0.09 2.06 ± 0.14d 2.05 ± 0.1d
mucin (μg/g tissue) 343.30 ± 16.91 213.29 ± 17.91b 303.34 ± 17.4e 295.06 ± 15.62e
  1. aStomach ulceration in mice was induced by oral administration of indomethacin (18 mg/kg). PK (20 mg/kg/day × 3 days) and Omez (3 mg/kg/day × 3 days) were used as the test samples. The assays were carried out on day three of ulceration, 4 h after the last dose of the drug. The values are mean ± SEM (n = 15). b P < 0.05, c P 0.001 compared to normal mice, d P < 0.05, e P < 0.01, f P < 0.001 compared to the group III mice.