The time course of stomach ulceration and its prevention by different doses of PK. Stomach ulceration in mice was induced by oral administration of indomethacin (18 mg/kg body weight). Different doses of PK were used for the experiments. The ulcer indices were measured on different days 4 h after the last dose of PK and the values are mean ± S.E.M. (n = 15). a
P < 0.01, b
P < 0.001 compared to 1st day ulcerated untreated mice; c
P < 0.01, d
P < 0.001 compared to the group III mice.