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Table 7 Effect of extract on leukocyte and macrophage migration in vivo

From: Acanthus montanus: An experimental evaluation of the antimicrobial, anti-inflammatory and immunological properties of a traditional remedy for furuncles

Extract

Dose (mg/kg)

Leukocyte Count

Macrophage Count (Cells/High Power Field)

  

TLC × 103 (Cells/ml)

Neutrophil Count (%)

 

Control

-

3.30 ± 1.6

55.0 ± 5.5

6.33 ± 0.88

AE

200

10.9 ± 3.2 (230.30)

73.0 ± 9.6 (32.73)

7.97 ± 0.38 (26.5)

 

400

10.0 ± 3.2 (203.03)

69.7 ± 12.0 (26.73)

9.53 ± 1.92 (50.8)

 

800

3.97 ± 2.4 (20.30)

52.7 ± 99.0 (-4.18)

14.20 ± 2.62* (125.4)

Levamisole

2.5

1.77 ± 0.3 (-46.36)

40.0 ± 6.2 (-27.27)

NT

Metronidazole

300

NT

NT

9.75 ± 0.9 (54.03)

  1. TLC = Total Leukocyte Count; Macrophage Count = Total number of cells per high power field; Values in parenthesis represent the percent migration of cells; NT = Not tested; AE = Aqueous extract; *P < 0.05 compared to Control (ANOVA; LSD post hoc)