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Table 3 Effect of CS on endogenous antioxidant and TBARS level in CMS rats

From: Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress

 

Groups

Parameters

Control

CMS

CMS+DZM (2 mg/kg, p.o)

CMS+CS

    

125 mg/kg, p.o

250 mg/kg, p.o

SOD (U/mg protein)

     

Brain

1.09 ± 0.03

0.21 ± 0.02**

0.98 ± 0.04††

1.30 ± 0.07††

1.54 ± 0.06††

Kidneys

0.75 ± 0.03

0.51 ± 0.05**

0.66 ± 0.05

0.71 ± 0.05††

0.88 ± 0.01††

Adrenals

0.99 ± 0.10

0.56 ± 0.04**

0.85 ± 0.07†

0.92 ± 0.09†

0.83 ± 0.06

CAT (U/mg protein)

     

Brain

1.77 ± 0.13

1.67 ± 0.28

1.50 ± 0.36

2.13 ± 0.41

2.63 ± 0.56

Kidneys

2.87 ± 0.35

1.43 ± 0.37*

1.83 ± 0.40

3.14 ± 0.24††

3.93 ± 0.14††

Adrenals

1.27 ± 0.15

0.25 ± 0.02**

0.8 ± 0.06††

0.41 ± 0.08

0.72 ± 0.09††

Ascorbic acid (μg/mg protein)

     

Brain

13.75 ± 3.50

14.25 ± 3.50

12.50 ± 3.13

10.38 ± 2.63

12.25 ± 3.13

Kidneys

17.83 ± 2.00

23.33 ± 1.67*

18.33 ± 1.50

20.50 ± 1.17

18.33 ± 0.67

Adrenals

43.33 ± 4.7

90.00 ± 11.33**

49.67 ± 6.53††

58.67 ± 9.13†

68.67 ± 6.67

TBARS (nmol of MDA/mg tissue)

     

Brain

0.15 ± 0.02

0.89 ± 0.12**

0.42 ± 0.10††

0.48 ± 0.07††

0.38 ± 0.09††

Kidneys

0.19 ± 0.02

0.84 ± 0.07**

0.53 ± 0.05

0.58 ± 0.04

0.38 ± 0.19††

Adrenals

0.28 ± 0.24

1.23 ± 0.13**

1.04 ± 0.21†

1.32 ± 0.28

1.09 ± 0.33†

  1. Data are expressed as mean ± SEM. * and † indicates statistical significance in comparison to control and stress groups respectively and denotes *, † p < 0.05 and **, † † p < 0.01
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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