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Table 2 Laboratory-based evaluations of safety

From: Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN25438351]

Test Glucosamine Wk. 0 Glucosamine Wk. 8 Reparagen Wk. 0 Reparagen Wk. 8
Neutrophils % 63.46 ± 1.25 63.54 ± 1.26 62.19 ± 1.32 62.38 ± 1.27
Lymphocytes % 31.73 ± 1.21 32.00 ± 1.27 32.27 ± 1.18 32.27 ± 1.21
Monocytes % 1.17 ± 0.14 1.32 ± 0.15 1.11 ± 0.13 1.16 ± 0.15
Eosinophils % 3.54 ± 0.36 3.22 ± 0.30 4.11 ± 0.47 3.19 ± 0.41
Basophils % 0.02 ± 0.02 0 ± 0 0 ± 0 0 ± 0
White blood cells mm 3 7929 ± 268 7515 ± 222 7753 ± 303 7496 ± 262
Red Blood Cells mm 3 4.06 ± 0.10 4.04 ± 0.08 4.13 ± 0.11 4.15 ± 0.08
Hemoglobin gm/dl 12.02 ± 0.3 12.00 ± 0.2 11.84 ± 0.3 11.92 ± 0.2
Erythrocyte Sedimentation Rate mm 33.0 ± 3.6 30.3 ± 3.0 33.9 ± 3.4 28.5 ± 3.1a
SGPT IU/L 26.3 ± 2.6 23.6 ± 1.7 22.9 ± 2.1 19.9 ± 1.3
Creatinine mg/dl 0.97 ± 0.03 0.93 ± 0.03 1.17 ± 0.21 0.93 ± 0.03
  1. Data expressed as a mean ± SEM.
  2. There was no difference between baseline and week 8 values for the treatment groups with the exception of erythrocyte sedimentation rate as denoted by the letter a (p < 0.05). As the analysis was done on a paired basis completion of the protocol was necessary, hence the analysis is per protocol, glucosamine n = 41, reparagen n = 38.