Figure 12
From: Novel phytoandrogens and lipidic augmenters from Eucommia ulmoides
In-vivo testosterone-E. ulmoides (EU) extract and ventral prostate growth in prepubertal male WISTAR rats. The synergistic augmenting effect of E. ulmoides on testosterone mediated prostate growth. Prepubertal male WISTAR rats were given IM testosterone injections of 5000 μg (Lane 2). To test synergism between E. ulmoides and an androgen, experimental rats were given saturating IM testosterone injections of 5000 μg in conjunction with oral gavaging of 50 mg of E. ulmoides (EU) extract (Lane 3). Control animals were given IM injections of olive oil plus concurrent oral gavaging of ethanolic water. Prostatic growth is expressed as the weight of the ventral prostate gland normalized to 100 g body weight of the individual rats. Each data point is mean ± SE of five animals' ventral prostate weights.