Potentials of leaves of Aspilia africana (Compositae) in wound care: an experimental evaluation

Table 3 Bleeding/clotting and whole rat blood coagulation time

Extract/fraction	Concentration (μg/ml)	Bleeding/clotting time (s)	Coagulation time (s)
ME	10	NT	102.67 ± 31.08
	100	31.33 ± 0.67^{a, b}	55.67 ± 8.95
HF	10	NT	115.00 ± 26.50
	100	42.00 ± 2.31^{a, b}	64.00 ± 25.53
MF	10	NT	98.33 ± 36.84
	100	30.33 ± 3.84^{a, b}	42.67 ± 2.40^a
Normal saline		54.00 ± 2.18	48.67 ± 5.20
Control		52.00 ± 0.58	89.33 ± 9.39

^{a, b} P < 0.05 compared to Control and normal saline respectively (ANOVA; LSD post hoc); Values of bleeding and coagulation time shown are Mean ± SEM (n = 3); ME = Methanol extract; HF = n-Hexane fraction; MF = Methanol fraction; NT = Not tested.

ISSN: 2662-7671