Group | N | Treatment (mg/kg/day) | Initial Arthritic Score | Final Arthritic Score |
---|
Control | 15 | N/A | 2.0 ± 0.13 | 2.63 ± 0.55 |
Perna | 12 | 100 | 2.2 ± 0.2 | 1.42 ± 0.24 a
|
DMG | 12 | 100 | 2.1 ± 0.17 | 2.71 ± 0.41 |
- CIA was induced and mice were treated as indicated. Initial and final arthritic scores were determined by averaging individual daily scores within a group (mean ± s.e.m.). The arthritic score was graded from 0–3: 0, no pathology; 1, swelling in one limb; 2, moderate swelling in multiple limbs with joint locking; and 3, pronounced swelling in all four limbs with joint locking. To determine statistical significance, treatment groups were compared to the control group and analyzed by the Kruskal-Wallis test. aindicates p < 0.05 compared to controls.