Figure 2From: Immunomodulation of murine collagen-induced arthritis by N, N-dimethylglycine and a preparation of Perna canaliculus Perna extract inhibits IL-12p40 and TNF-α production by monocytes. THP-1 human monocytes were primed with IFN-γ (10 ng/ml) then stimulated with LPS (1 μg/ml) in the presence of increasing concentrations of Perna extract. TNF-α (panel A) and IL-12p40 (panel B) concentrations were determined by ELISA. * indicates a p-value < 0.05.Back to article page