MAK-4 and -5 supplemented diet inhibits liver carcinogenesis in mice

Table 2 Dosage effect of MAK-4 and MAK-5 on H-ras-induced cell transformation in Rat 6 cells

Treatment	Exogenous H-*ras* gene	Cytotoxicity (% survival)	Relative number of foci
Mock control	-	100	0
None	+	100	1.0
MAK-4:
200 μg/ml	+	132	1.75
500 μg/ml	+	98	1.29
1000 μg/ml	+	92	1.35
MAK-5:
200 μg/ml	+	135	0.69
500 μg/ml	+	64	0.28
1000 μg/ml	+	48	0.26

Data were obtained from two individual experiments by focus formation assay. Triplicate plates were used for each experiment. Experimental procedures were the same as indicated in Table 1.

ISSN: 2662-7671