Table 3 Clinical outcomes 0–12 months

Disease Score (0–10)

155

5.95 (1.74)

2.31 (2.29)

p < 0.001

4.00 (3.50 to 4.50)

88%

1.52

Symptom Score (0–10)

184

5.74 (1.81)

3.04 (2.16)

p < 0.001

2.97 (2.50 to 3.25)

83%

1.05

SF-36 scales (0–100)

-Physical Function

161

77.09 (24.07)

84.41 (20.69)

p < 0.001

7.50 (5.00 to 10.00)

60%

0.37

-Role Physical

157

55.47 (38.39)

72.29 (36.64)

p < 0.001

25.00 (12.50 to 37.50)

46%

0.42

-Role-Emotional

157

68.15 (37.43)

81.63 (31.98)

p < 0.001

33.33 (16.67 to 33.34)

39%

0.33

-Social Functioning

161

67.93 (25.07)

77.10 (23.06)

p < 0.001

12.50 (6.25 to 18.75)

52%

0.34

-Mental Health

160

58.74 (18.25)

66.10 (18.34)

p < 0.001

8.00 (4.00 to 10.00)

63%

0.43

-Bodily Pain

161

59.89 (27.62)

71.27 (26.76)

p < 0.001

15.50 (9.50 to 21.00)

54%

0.38

-Vitality

160

42.53 (18.34)

52.84 (18.49)

p < 0.001

12.50 (10.00 to 17.50)

60%

0.53

-General Health

161

53.10 (19.30)

61.01 (19.48)

p < 0.001

8.50 (5.00 to 11.00)

63%

0.45

SF-36 Health Change (1–5**)

159

3.27 (1.08)

2.14 (1.02)

p < 0.001

1.50 (1.00 to 2.00)

65%

0.71

SF-36 Physical Component

154

44.01 (10.92)

47.99 (10.43)

p < 0.001

3.97 (2.71 to 5.30)

73%

0.42

SF-36 Mental Component

154

42.34 (11.98)

46.84 (10.47)

p < 0.001

3.98 (2.30 to 5.71)

64%

0.40

KINDL subscales (0–100)

-Psychic

16

69.75 (19.91)

69.74 (21.57)

p = 0.782

1.13 (-4.55 to 5.68)

56%

0.00

-Somatic

16

71.18 (17.21)

71.74 (19.88)

p = 0.520

2.78 (-4.16 to 8.33)

63%

0.03

-Social

16

74.30 (14.89)

69.73 (18.78)

p = 0.292

-4.16 (-9.72 to 3.65)

31%

-0.26

-Function

15

67.42 (12.08)

69.18 (14.45)

p = 0.367

2.04 (-3.41 to 6.82)

67%

0.20

KINDL Summary Score (0–100)

16

70.39 (17.67)

69.77 (17.91)

p = 0.889

0.31 (-4.02 to 4.93)

50%

-0.06

KITA subscales (0–100)

-Psychosoma

31

62.23 (19.76)

76.44 (13.62)

p = 0.001

13.54 (4.17 to 21.87)

77%

0.62

-Daily Life

29

63.22 (12.40)

67.96 (15.43)

p = 0.038

6.25 (0.00 to 12.50)

55%

0.28