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Table 3 Experiment A: Carrageenan edema and administration by sub plantar injection

From: Rat models of acute inflammation: a randomized controlled study on the effects of homeopathic remedies

Drug

Paw volume increase over time (ml ± SD) and effect (% of negative control)

 

1 hr

 

3 hr

 

5 hr

 

7 hr

 

Saline

0.63 ± 0.09

 

0.92 ± 0.14

 

0.84 ± 0.13

 

0.81 ± 0.14

 

Arnica D4

0.59 ± 0.15

-7

0.90 ± 0.14

-2

0.86 ± 0.15

3

0.74 ± 0.15

-8

Apis D4

0.57 ± 0.08

-10

0.83 ± 0.14

-10

0.80 ± 0.13

-5

0.67 ± 0.12

-17

Atropa D4

0.61 ± 0.09

-4

0.96 ± 0.09

4

0.81 ± 0.10

-3

0.74 ± 0.15

-9

Hamamelis D4

0.62 ± 0.13

-3

0.95 ± 0.15

3

0.87 ± 0.17

5

0.69 ± 0.12

-15

Lachesis D6

0.64 ± 0.16

1

0.86 ± 0.22

-7

0.85 ± 0.20

2

0.81 ± 0.12

0

Phosphorus D6

0.59 ± 0.09

-8

0.94 ± 0.13

2

0.88 ± 0.16

6

0.74 ± 0.13

-9

Indomethacin i.m.

0.54 ± 0.12

-14

0.69 ± 0.12

-25

0.63 ± 0.11

-25

0.49 ± 0.05

-40

  1. ANOVA results. Treatment: F(7,86) = 8.55, p < 0.0001; Time: F(3,258) = 221.19, p < 0.0001; Treatment × time: F(21,258) = 3.18, p < 0.0001.
  2. Bold characters denote significant comparisons (by Student t test) vs. Saline group corresponding for time since edema induction.