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Table 1 General scheme of the study

From: Rat models of acute inflammation: a randomized controlled study on the effects of homeopathic remedies

   

Phase A

Phase B

Randomisation

     

   by cages

  

   within cages by treatments

  

-

Blinding

     

   Treatment administration

  

-

   Edema measurement

  

Inflammation model

  

CA

BL

CA

Homeopathic remedies

     
 

dilution

n. of animals studied

   

   Arnica

D4

71

O/I

O/I

-

   Apis

D4

90

O/I

O/I

O

   Apis

D30

18

-

-

O

   Atropa

D4

72

O/I

O/I

-

   Hamamelis

D4

72

O/I

O/I

-

   Lachesis

D6

86

O/I

O/I

O

   Lachesis

D30

18

-

-

O

   Phosphorus

D6

90

O/I

O/I

O

   Phosphorus

D30

18

-

-

O

Reference treatments

     

   Placebo:

     

Physiological solution

 

86

O/I

O/I

O

   Active comparator:

     

Indomethacin

 

88

I/I

I/I

I

  1. O = oral administration
  2. I = administration through injection
  3. CA = carrageenan induced edema
  4. BL = autologous blood induced edema
  5. Each treatment group has been tested through 3 replications. In each replication 6 rats were studied. In experiment A 11 rats were excluded from the analyses because of problems with edema induction.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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