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Table 2 Percent blood glucose reduction produced by T. chebula after chronic administration in streptozotocin-induced diabetic rats

From: Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats

Group (n = 5)

Dose (mg/kg)

Percent blood glucose reduction

  

1

2

3

4 (Weeks)

Control

----

-19.72 ± 8.05

-14.35 ± 4.92

-7.06 ± 4.28

-12.48 ± 7.55

T. chebula

300

38.75 ± 8.09*

45.20 ± 11.64*

48.10 ± 5.25*

53.09 ± 3.14*

Glibenclamide

0.04

48.09 ± 10.90*

55.75 ± 8.03*

58.88 ± 5.08*

60.10 ± 2.70*

  1. Values are represented as mean ± S.E.M.; n = number of animals per group
  2. Significant difference from control group at identical times, *P < 0.01