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Table 1 Percent blood glucose reduction produced by T.chebula after oral administration in streptozotocin-induced diabetic rats.

From: Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats

Group (n = 5)

Dose (mg/kg)

Percent blood glucose reduction

  

0.5

1

2

4

6

8

12 (hrs)

Control

---

-5.65 ± 1.80

-8.10 ± 3.29

-1.35 ± 6.62

-12.09 ± 4.48

-7.25 ± 4.90

-4.19 ± 2.08

-7.03 ± 8.15

T.chebula

100

-2.18 ± 3.95

8.45 ± 9.27

17.82 ± 5.38*

20.85 ± 5.29*

19.94 ± 6.18*

10.98 ± 8.54

8.36 ± 3.18

T.chebula

200

1.28 ± 4.72

20.28 ± 6.29*

31.98 ± 8.24**

28.45 ± 6.20**

26.55 ± 2.70**

18.25 ± 5.21*

12.86 ± 8.20*

T.chebula

300

-1.18 ± 4.25

25.88 ± 10.05**

38.92 ± 7.18**

42.20 ± 4.65**

33.09 ± 8.05**

27.85 ± 4.78**

22.90 ± 7.55**

Glibenclamide

0.04

24.92 ± 8.20*

32.37 ± 4.60**

38.72 ± 10.22**

50.44 ± 8.40**

46.56 ± 4.60**

23.11 ± 6.75*

10.26 ± 11.03

  1. Values are represented as mean ± SEM.; n = number of animals per group
  2. Significant difference from control group at identical times, *P < 0.01; **P < 0.001