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Table 1 Effect of Lantana camara leaf powder, LCME, lantadene A and neostigmine on small intestinal transit in mice.

From: Evaluation of antimotility effect of Lantana camara L. var. acuelata constituents on neostigmine induced gastrointestinal transit in mice

Treatment

Total length of intestine (cm)

Distance traveled by charcoal (cm)

% Intestinal Transit

CMC Control

45.66 ± 6.24

21.66 ± 0.57

47.25 ± 6.10

Leaf Powder (1% for 10 days)

46.50 ± 6.19

15.50 ± 7.70

34.78 ± 3.52**

LCME (1 g/kg)

50.00 ± 0.90

0.50 ± 0.01

1.00 ± 0.01***

LCME (500 mg/kg)

53.66 ± 6.02

11.00 ± 6.02

26.46 ± 6.82***

LCME (250 mg/kg)

48.30 ± 1.36

15.30 ± 0.51

31.74 ± 1.49***

LCME (125 mg/kg)

49.00 ± 0.89

19.00 ± 3.58

38.67 ± 6.60***

Lantadene A (85 mg/kg)

44.00 ± 7.92

18.01 ± 7.37

39.47 ± 10.05**

Lantadene A (170 mg/kg)

47.00 ± 4.73

13.00 ± 3.03

27.34 ± 4.58**

Neostigmine (1 μg/kg)

49.00 ± 4.69

34.33 ± 9.15

69.30 ± 12.47***

Neostigmine (1 μg/kg)+LCME (1 g/kg)

48.00 ± 3.00

5.33 ± 0.76

11.10 ± 1.14***

Neostigmine (1 μg/kg)+LCME (500 mg/kg)

50.50 ± 0.70

12.00 ± 1.40

24.00 ± 2.19***

  1. Statistical analysis: Values are mean ± S.D. of 6 observations in each group. Values having P < 0.01 were considered significant. **P < 0.01, ***P < 0.001 as compared to control.