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Table 1 Effect of Lantana camara leaf powder, LCME, lantadene A and neostigmine on small intestinal transit in mice.

From: Evaluation of antimotility effect of Lantana camara L. var. acuelata constituents on neostigmine induced gastrointestinal transit in mice

Treatment Total length of intestine (cm) Distance traveled by charcoal (cm) % Intestinal Transit
CMC Control 45.66 ± 6.24 21.66 ± 0.57 47.25 ± 6.10
Leaf Powder (1% for 10 days) 46.50 ± 6.19 15.50 ± 7.70 34.78 ± 3.52**
LCME (1 g/kg) 50.00 ± 0.90 0.50 ± 0.01 1.00 ± 0.01***
LCME (500 mg/kg) 53.66 ± 6.02 11.00 ± 6.02 26.46 ± 6.82***
LCME (250 mg/kg) 48.30 ± 1.36 15.30 ± 0.51 31.74 ± 1.49***
LCME (125 mg/kg) 49.00 ± 0.89 19.00 ± 3.58 38.67 ± 6.60***
Lantadene A (85 mg/kg) 44.00 ± 7.92 18.01 ± 7.37 39.47 ± 10.05**
Lantadene A (170 mg/kg) 47.00 ± 4.73 13.00 ± 3.03 27.34 ± 4.58**
Neostigmine (1 μg/kg) 49.00 ± 4.69 34.33 ± 9.15 69.30 ± 12.47***
Neostigmine (1 μg/kg)+LCME (1 g/kg) 48.00 ± 3.00 5.33 ± 0.76 11.10 ± 1.14***
Neostigmine (1 μg/kg)+LCME (500 mg/kg) 50.50 ± 0.70 12.00 ± 1.40 24.00 ± 2.19***
  1. Statistical analysis: Values are mean ± S.D. of 6 observations in each group. Values having P < 0.01 were considered significant. **P < 0.01, ***P < 0.001 as compared to control.