Protective role of Scoparia dulcis plant extract on brain antioxidant status and lipidperoxidation in STZ diabetic male Wistar rats

Table 4 Changes in activities of glutathione peroxidase, glutathione-S-transferase and the levels of reduced glutathione in brain of normal and experimental rats

Groups	Glutathione peroxidase (Units^A/mg protein)	Glutathione-S-transferase (Units^B/mg protein)	Reduced glutathione (mg/100g tissue)
Normal	3.4 1± 0.20^a	5.62 ± 0.28^a	35.19 ± 2.21^a
Normal + SPEt (200 mg/kg)	3.80 ± 0.18^a	5.90 ± 0.28^a	37.12 ± 2.14^a
Diabetic control	1.01 ± 0.05^b	0.81 ± 0.02^b	15.20 ± 1.44^b
Diabetic + SPEt (200 mg/kg)	2.62 ± 0.15^c	2.10 ± 0.13^c	26.02 ± 2.01^c
Diabetic + Glibenclamide (600 μg/kg)	1.97 ± 0.12^d	2.04 ± 0.13^c	25.50 ± 2.10^c

Values are given as mean ± SD for 6 rats in each group.
Values not sharing a common superscript letter differ significantly at p < 0.05 (DMRT).
Duncan procedure, Range for the level 2.95, 3.09, 3.20, 3.22.
A – μg of GSH consumed/min.
B – μmoles of CDNB – GSH conjugate formed/min.

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