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Table 1 Influence of atropine, mepyramine and propranolol on the hypotensive response of T. arjuna in dogs.

From: Possible mechanisms of hypotension produced 70% alcoholic extract of Terminalia arjuna (L.) in anaesthetized dogs

Drug Dose (n = 6) Response
    After Antagonist
   Before Antagonist Atropine (1 mg) Mepyramine (20 µg) Propranolol (30 µg)
T. arjuna 5 mg/kg Hypotension NS NS NS
T. arjuna 6 mg/kg Hypotension No Blockade No Blockade Blockade
T. arjuna 8 mg/kg Hypotension NS NS NS
T. arjuna 10 mg/kg Hypotension NS NS NS
T. arjuna 15 mg/kg Hypotension NS NS NS
T. arjuna 20 mg/kg(n = 2) Severe Hypotension NS NS NS
  1. NS – not studied; n – number of animals.