Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 3 Mean activities of lipid peroxidase (nMol MDA/gm wet tissue), acid and alkaline phosphatase activities (in terms of mM Phenol liberated/100 mg protein after 30 min of incubation at 37°C), in different organs of mice treated with p Dimethylaminoazobenzene (DAB) + Phenobarbital (PB), DAB + PB + Chelidonium (Ch)-30 and DAB + PB + Chelidonium (Ch)-200 against their normal and phenobarbital control.

From: Effect of a homeopathic drug, Chelidonium, in amelioration of p-DAB induced hepatocarcinogenesis in mice

   Lipid peroxidase activity Alkaline phosphatase activity Acid phosphatase activity
Fixation Interval (Days) Series Liver   Kidney   Spleen   Liver   Kidney   Spleen   Liver   Kidney   Spleen  
   Activity ± SE % Prot. Activity ± SE % Prot. Activity ± SE % Prot. Activity ± SE % Prot. Activity ± SE % Prot. Activity ± SE % Prot. Activity ± SE % Prot. Activity ± SE % Prot. Activity ± SE % Prot.
  Normal 18.72 ± 1.27   16.67 ± 0.26   25.44 ± 0.68   0.09 ± 0.01   0.12 ± 0.03   0.09 ± 0.01   0.10 ± 0.002   0.09 ± 0.004   0.10 ± 0.003  
  PB 16.58 ± 0.43   15.85 ± 1.39   17.35 ± 0.45   0.11 ± 0.001   0.11 ± 0.004   0.11 ± 0.002   0.18 ± 0.02   0.15 ± 0.02   0.15 ± 0.02  
60 DAB +PB 117.48 ± 3.80   134.41 ± 1.08   207.95 ± 3.01   0.28 ± 0.04   0.25 ± 0.02   0.15 ± 0.01   0.30 ± 0.03   0.29 ± 0.05   0.27 ± 0.04  
  DAB+PB+Ch30 24.26 ± 0.78 93.22a 29.04 ± 1.05 105.37c 44.32 ± 1.14 163.63b 0.11 ± 0.03 0.17 0.22 ± 0.01 0.03 0.07 ± 0.03 0.07a 0.30 ± 0.03 0 0.30 ± 0.05 0.01 0.26 ± 0.03 0.01
  DAB+PB+Ch200 84.67 ± 0.27 32.81 19.737 ± 0.45 114.67 48.71 ± 3.28 159.24b 0.05 ± 0.03 0.22 0.28 ± 0.04   0.04 ± 0.01 0.11 0.24 ± 0.03 0.06 0.22 ± 0.04 0.07 0.30 ± 0.03 0.03
  Normal 18.72 ± 1.27   15.85 ± 1.39   25.44 ± 0.68   0.09 ± 0.01   0.12 ± 0.03   0.09 ± 0. 01   0.10 ± 0.002   0.09 ± 0.004   0.10 ± 0.003  
  PB 25.21 ± 0.31   16.58 ± 0.62   21.88 ± 0.98   0.11 ± 0.002   0.12 ± 0.003   0.11± 0. 003   0.19 ± 0.003   0.18 ± 0.01   0.18 ± 0.003  
90 DAB +PB 69.25 ± 0.75   61.42 ± 0.61   91.99 ± 5.20   0.24 ± 0.04   0.27 ± 0.04   0.17± 0. 01   0.36 ± 0.04   0.30 ± 0.01   0.24 ± 0.02  
  DAB+PB+Ch30 48.77 ± 3.07 20.48 22.12 ± 0.76 39.30c 30.95 ± 3.36 61.04c 0.04 ± 0.01 0.19 0.26 ± 0.05 0.01 0.06 ± 0. 04 0.11a 0.32 ± 0.07 0.04 0.29 ± 0.04 0.01 0.28 ± 0.04 0.04
  DAB+PB+Ch200 135.74 ± 0.22 -66.49 22.18 ± 0.64 39.24b 30.49 ± 0.75 61.51c 0.14 ± 0.06 0.09 0.34 ± 0.02   0.09 ± 0. 04 0.08 0.30 ± 0.04 0.06 0.29 ± 0.02 0.01 0.30 ± 0.04 0.06
  Normal 18.72 ± 1.27   15.85 ± 1.39   25.435 ± 0.68   0.09 ± 0.01   0.12 ± 0.03   0.09 ± 0. 01   0.10 ± 0.002   0.09 ± 0.004   0.10 ± 0.003  
  PB 38.63 ± 2.79   44.96 ± 1.49   28.72 ± 0.65   0.14 ± 0.003   0.12 ± 0.01   0.17 ± 0. 002   0.20 ± 0.001   0.15 ± 0.01   0.18 ± 0.001  
120 DAB+PB 165.43 ± 1.92   138.65 ± 2.09   274.55 ± 1.08   0.19 ± 0.02   0.31 ± 0.02   0.15 ± 0. 02   0.40 ± 0.07   0.34 ± 0.05   0.29 ± 0.03  
  DAB+PB+Ch30 113.04 ± 1.14 52.39a 89.79 ± 0.48 48.86 92.56 ± 0.18 181.99c 0.19 ± 0.003 0.001 0.27 ± 0.05 0.04 0.15 ± 0. 003 0.01 0.50 ± 0.05 0.1 0.67 ± 0.09 0.33 0.22 ± 0.05 0.06
  DAB+PB+Ch200 190.25 ± 0.48 -25.82 18.21 ± 0.48 120.45b 110.51 ± 0.36 160.04c 0.08 ± 0.01 0.102 0.15 ± 0.06 0.16a 0.10 ± 0. 01 0.05a 0.28 ± 0.02 0.12a 0.16 ± 0.02 0.17 0.24 ± 0.01 0.05
  1. SE= Standard error, a =p < 0.05, b= p < 0.01, c= p < 0.001. Prot. = Protection given by the drug.